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Tizanidine Side Effects | Seizures, Anxiety, Insomnia

Tizanidine is a drug that’s only available with a prescription. It comes as an oral tablet and oral capsule, and the tablet is also known by its brain name Zanaflex. The drug is used to manage muscle spasms, and symptoms, which may include pain, stiffness, or muscle tightness. The medicine also treats individuals struggling with muscle spasticity, multiple sclerosis, and spinal cord injuries. Tizanidine falls under a classification of drugs known as alpha-2-adrenergic agonists. Tizanidine reduces nerve activity in the spinal cord, which helps to reduce muscle spasms. As you should expect from most drugs, Tizanidine produces side effects. While some may be moderate, others may be more severe.

Tizanidine Side Effects

The most common side effects of Tizanidine include:

  • Constipation
  • Drowsiness
  • Tiredness
  • Dry mouth
  • Weakness
  • Dizziness
  • Anxiety
  • Insomnia
  • Urinary tract infection
  • Trouble speaking
  • Vomiting
  • Sore throat
  • Runny nose
  • Vision problems

If you experience mild effects, you can assume they’ll dissipate in a few days or couple weeks. If you are dealing with more severe side effects that linger on, you must speak with your doctor or pharmacist immediately and start discussing alternatives.

Severe Tizanidine Side Effects

Although Tizanidine is considered a safe treatment for muscle spasms, some individuals will experience adverse effects during the use of the medication. You must call your doctor immediately if you notice severe side effects. If you believe these symptoms are life-threatening, do not hesitate to call 911 in case of a medical emergency. Some severe side effects of the drug you must watch out for include:

  • Hallucinations (seeing things that aren’t real)
  • Delusions (believing things that are not real)
  • Extremely low blood pressure
  • Dizziness or lightheadedness after sitting or lying down
  • Liver damage
  • Increased bleeding
  • Seizures
  • Bruising
  • Jaundice (yellowing of your skin and the whites of your eyes)

It’s crucial to note that drugs affect everyone differently, and we cannot guarantee that all of this information provides every side effect you may experience. You must always discuss possible side effects with your healthcare provider who is familiar with your medical history.

Tizanidine May Interact With Other Medications

If you are using certain herbs, vitamins, or medications, you must inform your treating physician as Tizanidine may adversely interact with these substances. An interaction is when something you are taking changes in how a drug works. It may be harmful or prevent the drug from working correctly. The only way to avoid this is by speaking with your doctor.

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Tizanidine Allergic Reaction

Some individuals who use Tizanidine may have an allergic reaction, which can be severe in some cases. As we described above, if you feel you are experiencing life-threatening symptoms, you must call 911 immediately. Allergy symptoms include:

  • Swelling of your throat or tongue
  • Itching
  • Trouble breathing

Do not take Tizanidine if you’ve had a previous allergic reaction as it could be fatal.

Tizanidine and Alcohol

Those who use this drug must avoid alcohol – drinks that contain alcohol will increase the amount of Tizanidine in your system, which can cause an increased level of side effects.

Sources

Chaudhury, S. (2010, January). Hallucinations: Clinical aspects and management. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105559/

Jaundice | Icterus. (2019, October 22). Retrieved from https://medlineplus.gov/jaundice.html

Tizanidine: MedlinePlus Drug Information. (n.d.). Retrieved from https://medlineplus.gov/druginfo/meds/a601121.html

Giovannitti, J. A., Thoms, S. M., & Crawford, J. J. (2015). Alpha-2 adrenergic receptor agonists: a review of current clinical applications. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389556/

Multiple Sclerosis. (2019, November 19). Retrieved from https://nccih.nih.gov/health/multiple-sclerosis

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